Advancements in Retrieval-Augmented Generation for Biomedical Applications

The field of biomedical research is witnessing significant advancements in the development of Retrieval-Augmented Generation (RAG) systems. These systems aim to improve the accuracy and reliability of large language models (LLMs) in generating responses to complex biomedical questions. Recent studies have focused on enhancing the robustness of RAG systems to adversarial evidence, improving their ability to abstain from answering questions when uncertain, and developing more effective methods for retrieving relevant technical documents. Notably, the integration of energy-based models and Rescorla-Wagner steering has shown promise in improving the reliability and trustworthiness of LLMs in real-world applications. Furthermore, the use of ensemble methods and zero-shot question answering has demonstrated state-of-the-art performance in biomedical question answering tasks. Overall, these advancements have the potential to significantly improve the accessibility and comprehension of biomedical information, paving the way for more accurate and reliable public health communication. Noteworthy papers include: Speaking at the Right Level, which proposes a Controlled-Literacy framework for generating tailored counterspeech adapted to different health literacy levels. Trusted Uncertainty in Large Language Models presents UniCR, a unified framework for confidence calibration and risk-controlled refusal, which has shown consistent improvements in calibration metrics and lower area under the risk-coverage curve.

Sources

CaresAI at BioCreative IX Track 1 -- LLM for Biomedical QA

Speaking at the Right Level: Literacy-Controlled Counterspeech Generation with RAG-RL

Trusted Uncertainty in Large Language Models: A Unified Framework for Confidence Calibration and Risk-Controlled Refusal

Evaluating the Robustness of Retrieval-Augmented Generation to Adversarial Evidence in the Health Domain

Enhancing Technical Documents Retrieval for RAG

Energy Landscapes Enable Reliable Abstention in Retrieval-Augmented Large Language Models for Healthcare

Context Engineering for Trustworthiness: Rescorla Wagner Steering Under Mixed and Inappropriate Contexts

Biomedical Literature Q&A System Using Retrieval-Augmented Generation (RAG)

LLM Ensemble for RAG: Role of Context Length in Zero-Shot Question Answering for BioASQ Challenge

Built with on top of