Advances in Digital Pathology and Microscopy

The field of digital pathology and microscopy is rapidly advancing, with a focus on developing innovative methods for image analysis, segmentation, and classification. One of the key trends is the use of deep learning techniques, such as convolutional neural networks (CNNs) and graph neural networks (GNNs), to improve the accuracy and efficiency of image analysis. Another area of research is the development of virtual staining methods, which can reduce the need for physical staining and improve the quality of images. Additionally, there is a growing interest in the use of hyperspectral imaging and spatial transcriptomics to gain a better understanding of the underlying biology of tissues and cells. Notable papers in this area include the introduction of Spotlight, a virtual staining approach that guides the model to focus on relevant cellular structures, and USIGAN, a method for IHC virtual staining that extracts global morphological semantics without relying on positional correspondence. Omni-Fuse, a spatial-spectral omni-fusion network for hyperspectral image segmentation, is also a significant contribution. EXAONE Path 2.0, a pathology foundation model that learns patch-level representations under direct slide-level supervision, and GNN-ViTCap, a framework for whole slide image classification and captioning, are other noteworthy papers.

Sources

Foreground-aware Virtual Staining for Accurate 3D Cell Morphological Profiling

Normal Patch Retinex Robust Alghoritm for White Balancing in Digital Microscopy

USIGAN: Unbalanced Self-Information Feature Transport for Weakly Paired Image IHC Virtual Staining

Omni-Fusion of Spatial and Spectral for Hyperspectral Image Segmentation

EXAONE Path 2.0: Pathology Foundation Model with End-to-End Supervision

Learning from Sparse Point Labels for Dense Carcinosis Localization in Advanced Ovarian Cancer Assessment

GNN-ViTCap: GNN-Enhanced Multiple Instance Learning with Vision Transformers for Whole Slide Image Classification and Captioning

Integrating Pathology Foundation Models and Spatial Transcriptomics for Cellular Decomposition from Histology Images

CL-Polyp: A Contrastive Learning-Enhanced Network for Accurate Polyp Segmentation

X-RAFT: Cross-Modal Non-Rigid Registration of Blue and White Light Neurosurgical Hyperspectral Images

THUNDER: Tile-level Histopathology image UNDERstanding benchmark

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